Mark Dumont
mark_dumont@urmc.rochester.edu
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MPSBC
is one of 9 membrane protein structure determina- tion centers
established in July 2010 as part of the NIGMS PSI:Biology
Initiative.
MPSBC's Mission:
MPSBC aims to establish a pipeline
to generate multiple target constructs for expression studies followed
by pre-crystallization screening to identify stable protein:detergent
complexes. The complexes then undergo high-throughput crystallization
screening and optimization followed by structure determination. Targets
include transporters, transmembrane enzymes involved in lipid synthesis
and lipid attachment, and membrane protein complexes.
Community Outreach:
MPSBC offers assistance with protein
production, pre-crystallization screening, and high-throughput
crystallization.
Contact
MPSBC:
Dr. Michael
Malkowski, Hauptman-Woodward Medical Research Inst.
700 Ellicott Street, Buffalo, NY 14203-1102. Tel: 716 898 8624 |
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